Sodium Starch Glycolate

Sodium Starch Glycolate (CAS No. 9063 – 38 – 1) Is The Sodium Salt Of A Carboxy Methyl Ether Of Starch. The Molecular Weight Is Typically 500000 – 11000000. It Is Available In Both The Form That Is Processed From Maize And Processed From Potato.

Very Fine White Or Off White Free Flowing Powder, Odourless Or Almost Odourless Practically Insoluble In Water, Insoluble In Most Prganic Solvents.  It Consists Of Oval Or Spherical Granules 30 – 100 Nm In Diameter With Some Less Spherical Granules Ranging From 10-35 Ium In Diameter.

Applications :

• Sodium Starch Glycolate Is Widely Used In Oral Pharmaceuticals As A Disintegrant In Capsule And Tablet Formulations. It Is Recommended To Use In Tablets Prepared By Either Direct –COMPRESSION Or Wet Granulation Processes.
• The Recommended Concentration In A Formulation Is 2 – 8 % With The Optimum Concentration About 4% Although In Many Cases 2% Insufficient.
• Disintegration Occurs By Rapid Uptake Of Water Followed By Rapid And Enormous Swelling. The Disintegrant Efficiency Of Sodium Starch Glycolate Is Unimpaired In The Presence Of Hydrophobic Excipients, Such As Lubricants Unlike Many Other Disintegrants. Increasing The Tablet Compression Pressure Also Appears To Have No Effect On Disintegration Time. Sodium Starch Glycolate Has Also Been Investigated For Use As A Suspending Vehicle

Stability And Storage Conditions : Tablets Prepared With Sodium Starch Glycolate Have Good Storage Properties. Sodium Starch Glycolate Is Stable And Should Be Stored In A Well –CLOSED Container To Protect It From Wide Variations In Humidityemperature That May Cause Caking. The Physical Properties Of Sodium Starch Glycolate Remain Unchanged For Upto 4 Yrs If Stored At Moderate Temperature And Humidity.

Packing: It Is Available In Export Worthy Bag Or Drum Packing As Per Our Customers Choice